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pentobarbital will lessen the extent or result of larotrectinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism.pentobarbital will minimize the extent or result of felodipine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.Induction of microsomal enzymes by this drug, may possibly shorten the 50 %-lifetime of do